This part of algorithm outlines the treatment methods of Mirena. The Mirena’s hormone cylinder dissolves and thus releases progestin levonorgestrel directly into the uterus. Its primary use is to prevent pregnancy, but it also treats heavy menstrual bleeding, PCOS, and endometriosis. When the Mirena is inserted into the uterus it gradually releases progestin, a synthetic progesterone, mimicking the natural hormones produced by the ovaries. The progestin begins to reduce the thickness of the uterine lining and after three months, the suppression of tissue growth not only prevents pregnancy, it also reduces menstrual bleeding, as well as prevents scar tissue from forming easing endometriosis symptoms, such as pelvic inflammation and bleeding. In addition, the progestin causes the cervical mucus to thicken, preventing that formation of tissue, such as cysts, thus treating PCOS, while also preventing sperm from entering the uterus and preventing pregnancy.


“Mirena Releasing Intrauterine System: Side Effects, Interactions, Warning & Uses.” 2017. RxList.

Monteiro, Ilza, et al. 2002. “Therapeutic Use of Levonorgestrel-Releasing Intrauterine System in Women with Menorrhagia: A Pilot Study.” Contraception 65: 325–328.

Office on Women’s Health, US Department of Health and Human Services. Polycystic Ovary Syndrome. Web. Retrieved 02/19/2018.

Scaccia, A. 2017. Will Mirena Help Treat Endometriosis or Make it Worse?